Since 2006, the annual total sales of the natural raw materials paclitaxel injection and semi-synthetic paclitaxel injection paclitaxel reached $ 3.7 billion in international market. It ranks top one in international anti-cancer drugs.
After listing in 1992, paclitaxel has been warmly welcomed by the medical profession. The record of annual sales is more than two hundred million U.S. dollars. In the seventh year, global market sales have exceeded $ 1 billion. Thus, the taxol create a sales miracle of a single preparation of the plant anti-cancer drugs, even if the other plants listed earlier anti-cancer drugs, with sales so far, only more than two hundred million U.S. dollars.
So far, the international market, only two kinds of paclitaxel bulk drugs: one from a variety of yew bark; another is extracted from ornamental yew branches in Europe 10-berry red mold base, and then by the semi-synthetic made, namely docetaxel, its structure and natural extract is very similar to paclitaxel. These two bulk drugs are the best-selling API products in the international pharmaceutical market, and a long period of short supply, according to estimates, sales of paclitaxel and docetaxel drug substance ratio of about 10:1.
Taxol anticancer drugs are the hospital of choice in the world. The incidence of tumors of the world in recent years has increased more than 10 years ago, nearly double the lung, breast and ovarian cancer and other malignant tumors also showed multiple trends, the main users of these are paclitaxel in cancer patients. Generally speaking, prior to take its place in no kind of plant anticancer drug paclitaxel sales will only rise, not fall.
According to the latest figures released by the World Health Organization, the United States has now become the world’s first cancer-prone countries, and its new cancer cases each year 1.4 million people, accounting for the 14% of the global cancer patients. The United States has still paclitaxel largest consumer. U.S. cancer incidence rates have increased, the main drug of paclitaxel against advanced cancer, you can believe that its sales will continue to maintain the chia seed momentum of rapid increase. United States and other developed countries in the ten years of clinical use of the process already summed up a set of Taxol and other anticancer drugs, the best compatibility program, its medical department has been inseparable from paclitaxel, therefore, the demand for paclitaxel The amount also was a corresponding rise in the trend.
In recent years, the use of paclitaxel in the medical device is also favored. U.S. medical device manufacturers in the development of a paclitaxel-eluting stent for the treatment of severely blocked coronary patients. This new drug-eluting stents to prevent blood lipids re-deposition in the formation of a new blockage of the stent surface, which can greatly improve the life of the pharmaceutical raw materials stent. Because this drug-eluting stent has become the best-selling products to international involvement in the treatment of medical devices on the market, it was predicted that paclitaxel was introduced to the medical device industry will greatly exacerbated by the international pharmaceutical industry intensified paclitaxel battle degree.
The reason that why paclitaxel can not be further expanded is related with the low content in yew bark. Basically every 10,000 kg of yew bark can extract 1 kg of paclitaxel. This mode of production is bound to destroy the valuable forest resource yew bark which is endangered. But the good news is that the long-term shortage of paclitaxel deadlock is improving. A few years ago, some foreign manufacturers already successful develop the cell culture batch cultivation of yew bark cells. Italy, the United Kingdom, the Netherlands and other Western countries are engaged in the cell culture production of taxol. Source:http://www.cospcn.com
Tag: Netherlands
Facts About Skin Cancer
According to Dr. Jan Nico Bouwes Bavinck, an individual of the leading researchers in a examine on cigarette smoking and skin cancer at Leiden University Health Center in the Netherlands, cigarette smoking far more than triples the possibility of acquiring squamous cell carcinoma. The study’s data indicated that using tobacco may possibly inhibit immune technique operate, leaving skin vulnerable to the cancer resulting in chemical compounds discovered in cigarette smoke.
Using tobacco lowers obtainable oxygen to the skin. Stats say that oxygen provide to skin is decreased for near to an hour soon after smoking for just 10 minutes. Skin cells are broken by the deprivation. Nicotine’s effect of narrowing blood vessels and minimizing circulation also damages skin cells. Using tobacco also thins the skin and interferes with healing.ng.
Gurus say that alcohol is the 2nd biggest possibility factor for oral cancer. When precisely how alcohol functions is unexplained, there are theories. It is thought that the liver damage introduced on my alcohol leads to cellular alterations. These mobile changes may well lead to modifications in the tissues of the mouth and throat.
A second concept is that alcohol boosts hormone amounts. There have been a huge amount of studies displaying the hyperlink involving improved levels of particular hormones and the incidence of cancer. According to statistics by the American Cancer Society, drinkers are six periods extra likely to be diagnosed with oral cancers than people who abstain from alcohol use.
When alcohol is blended with using tobacco, the incidence of cancer is even greater. Cells dehydrated by alcohol are much more vulnerable to cigarette’s cancer leading to chemical compounds. In accordance to gurus, you can reduced your risk of cancers by giving up cigarettes and minimizing or stopping alcohol use. It takes approximately 10 a long time for your risk degree to return to that of a nonsmoker and nondrinker.
If you imagine you are risk-free since you only drink or smoke socially, consider yet again. As handful of as two drinks a day for guys and 1 drink a day for gals is enough to enhance your risk. With so several cancer leading to chemical substances in cigarettes, a single smoke can do damage to the skin and raise your threat of skin cancer.
Cancer that is shaped in the tissues of the skin is regarded as Skin Cancer. It is a single of the most popular kinds of cancer that impacts guys and girls. This cancer has an effect on about a million individuals each and every 12 months and there are quite a few aspects that lead to this together with excessive sun coverage, tanning, weak immune techniques, and so on. Examine on to get a full awareness of this most widespread form of cancer and on actions to avoid it.
How is skin cancer prompted?
When the skin cells modify and multiply in an abnormal style, the uncontrollable growth brings about the advancement of a mass identified as a tumor. This tumor that occurs in the skin is also regarded as a lesion and these cancerous growths are malignant in nature which leads to the destruction of adjacent cells main to random progress. These tumors flow via the blood stream and influence other remote organs also in the course of the superior phases of skin cancer.
Janet Vafaie, dermatologist created Westwood Dermatology and has been proividing cancer screening at no charge to the residents of Westwood and surounding areas. She also in particularly expert in cosmetic and age rejuvination. She is the greatest of the Very best in thw Westwood place when you are searching for a Dermatologist. End by our office right here at Westwood Dermatology and learn much more.
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Purple Awareness Pins To Celebrate National Cancer Survivors Day
National Cancer Survivors Day is an annual holiday dedicated to celebrating life after cancer diagnosis. Managed by the National Cancer Survivors Day Foundation, this holiday is held on the first Sunday in June each year. National Cancer Survivors Day 2011 was held on June 5th. Started in 1988, this year’s National Cancer Survivors Day marks the holiday’s 23rd anniversary. Originally held solely in the United States, holiday celebrations now also take place in Canada, India, the Netherlands and many other nations around the world.
Thanks to medical research and early detection, the number of cancer survivors has increased dramatically over the past decades. According to the Centers for Disease Control and Prevention, while there were 3 million cancer survivors in 1971, the figure for 2007 was 11.7 million of people who are living with this disease.
Though National Cancer Survivors Day is observed internationally, most festivities are local celebrations. These are often sponsored by hospitals, cancer research facilities and other organizations committed to the cause. It’s also common for other cancer awareness causes to be represented at holiday gatherings, armed with sign-ups for events like the Susan G. Komen Foundation’s Race for the Cure. Events held for National Cancer Survivors Day include fundraisers, carnivals, speeches, concerts and art exhibits. Most events are designed for all ages, so it’s a great idea to bring the entire family along.
This holiday is as much for cancer survivors as it is for those still fighting. For patients still struggling with cancer, seeing and participating in the day’s events can help remind them that they’re not alone and that there’s hope. Look out for purple bracelets in the crowd; these are worn as a badge of honor by cancer survivors. Since many National Cancer Survivors Day events are locally-based, they also provide a great opportunity to meet new friends and supporters right in your own backyard.
Attending National Cancer Survivors Day parades or other events in your area is a great way to show your support for friends and loved ones who have been diagnosed with cancer. Just as cancer survivors typically wear purple bracelets, supporters can often be found wearing cancer awareness pins. Awareness ribbon pins are especially popular, as these can help show which type of cancer a loved one is battling. For example, pink ribbons represent the fight against breast cancer while teal ribbons support ovarian cancer. While supportive clothing and accessory items are not required to take part in National Cancer Survivors Day, they are a nice way to show some added support for the heroes this holiday honors.